United States securities and exchange commission logo February 23, 2024 David M. Urso President & Chief Executive Officer MEI Pharma, Inc. 11455 El Camino Real Suite 250 San Diego, California 92130 Re: MEI Pharma, Inc. Registration Statement on Form S-3 Filed February 20, 2024 File No. 333-277201 Dear David M. Urso: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Tim Buchmiller at 202-551-3635 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Justin W. Chairman, Esq.